The fascinating thing about this force is, as I discovered over the years, that it actually determines the wear and tear of all the relevant structures as mentioned above. Thus if a disc degenerates and bulges or ruptures, it is most likely that it does so because of weakness of this vital anti-gravitational force. For the spinal discs and joints, nothing matters more than this force because the lack of it puts strain on them and the abundance of it relieves them from tension, creating flexibility and well-being.Another fascinating aspect is that this anti-gravitational vital force can be increased through specific massages (passive treatment) and yogic exercises (active treatment). These treatments form an integral part of the Ali Technique for Backache. Most people who do spinal or general exercises, increase the general tone of muscles which form a minor part of the anti-gravitational force, indeed might actually increase it like guy ropes. Increase in posture-controlling muscle tone, however, relieves pain and removes some pressure from the affected or damaged discs, giving much needed relief in backache.This force is weakened by a series of factors ranging from bad posture to fatigue to excess body weight with sluggish muscles. The reduction of this force leads to increased pressure on the spinal joints and discs, which in turn lead to inflammation of their surfaces causing pain and discomfort.*56\330\8*
Naturally failing immune systems and naturally overactive immune systems have been blamed as noninfectious causes of chronic disease. But does it make sense that evolution would have generated such a complex system of checks and balances if these complexities were only to generate the system’s downfall? Imagine making an extravagant security guard system that self-destructs without provocation. We would not expect people to select the ineffective complex system over a more effective simple system. If an extravagant immunological security system self-destructed, then natural selection similarly would favor the simpler system. The more extravagant system wouldn’t be reproduced. We can expect that natural selection will not favor added complexity to immunological security systems when the increased complexity destroys the body without provocation. The immune system may, however, be driven to self-destructive tendencies through the ever-changing strategies of the burglars it is attempting to deter. Streptococcus pyogenes, for example, may damage the heart because one of the germ’s proteins has evolved camouflage that makes it look so much like a protein on the human heart that the immune response against the bacteria attacks the heart. In the absence of such provocation, though, the immune system is the quintessence of efficiency and flexibility.*22\225\2*
QUESTIONS ABOUT DRUGS FOR RHEUMATOID ARTHRITIS TREATMENT: FOLIC ACID, METHOTREXATE AND SULFASALAZINE
What is folic acid?Folic acid is a vitamin that is usually supplemented in those taking methotrexate to reduce the side effects.
Who should not take this drug?People with liver and kidney problems, diabetes, immune system disorders, and high alcohol intakes should not take this drug. Pregnant women, women intending to get pregnant and nursing women should not be started on the drug. Women planning to conceive a child should wait at least one menstrual period after stopping methotrexate before trying. Men planning to father children should not take the drug both because it might affect fertility and because it could be harmful to the baby.
Does methotrexate interact with other drugs?Yes, it does. Evidence exists that the new COX-2 drugs increase the blood levels of methotrexate. In fact, the elderly with decreased kidney function should not take the drug. Almost every NSAID will increase the potential for problems with this agent; however, under the care of your doctor, this should not be a problem. The doctor will test you periodically for potential problems.
What is sulfasalazine?This is a sulfa-containing agent useful for the treatment of arthritis. It is not terribly toxic, but it has greater toxicity than hydroxychloroquine.It is a good drug used in combination or by itself.The usual dose is 2 grams per day by mouth; however, your doctor will start you on a low dose to see how you fare on it. Some doctors will go to 3 grams per day, depending on any side effects experienced and how your arthritis progresses on the drug.Rashes, loss of appetite, and nausea are side effects experienced with this agent. Serious reactions are rare and include hepatitis, a lupus-like disease, and even a decrease of sperm counts. Your doctor should watch for these. Men should notify their doctors if they plan on fathering children so that the drug can be stopped or replaced with something else.*34/141/5*